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Something that struck me is that Pandora seems very perfect is certain ways (I'm not critising Avatar for it though). I mean bacteria and viruses or their Pandoran equivilents must certainly have evolved and what's stopping terran or Pandoran microbial life from spreading from one world to the other (humans couldn't have cured every disease by the time Avatar is set in, plus humans would have colonized Pandora long enough for the alien microbes to learn to infect them)? But maybe Ewya somehow doesn't permit the evolution of infectious diseases, but that would go against evolution...